Foram tratados 155 pacientes do sexo masculino, portadores de uretrite gonocócica aguda, com 3,0 g de Hetacilina K por via oral (70 casos) ou 1,0 g do mesmo medicamento por via intramuscular (85 casos). Em 88,6% dos casos tratados pela via oral, e em 93% dos casos tratados com uma injeção intramuscular, o corrimento desapareceu em um tempo médio de 48 horas. Não foram observadas reações de intolerância ao medicamento.

Schemes of treatment with one single parenteral injection or single oral dosis of a broad spectrum antibiotic - Hetacillin - has been employed in 155 patients with acute gonorrhoeae who were, then, followed-up during 15 days in the Service of VD of the School of Public Health, University of São Paulo. The diagnosis and control of the cases were performed through smears and cultures of the urethral discharge. Cure has been attained in 88,6% of 70 patients treated with 3.0 g of Hetacillin by oral route, in a single dosis, and in 93% of 85 patients treated with one single intramuscular injection of Hetacillin (1.0 g). Discharge has disappeared in an average of 48 hours in both schedules of treatment. No side effects or toxicity were observed.

Foram tratados 155 pacientes do sexo masculino, portadores de uretrite gonocócica aguda, com 3,0 g de Hetacilina K por via oral (70 casos) ou 1,0 g do mesmo medicamento por via intramuscular (85 casos). Em 88,6% dos casos tratados pela via oral, e em 93% dos casos tratados com uma injeção intramuscular, o corrimento desapareceu em um tempo médio de 48 horas. Não foram observadas reações de intolerância ao medicamento.

Schemes of treatment with one single parenteral injection or single oral dosis of a broad spectrum antibiotic - Hetacillin - has been employed in 155 patients with acute gonorrhoeae who were, then, followed-up during 15 days in the Service of VD of the School of Public Health, University of São Paulo. The diagnosis and control of the cases were performed through smears and cultures of the urethral discharge. Cure has been attained in 88,6% of 70 patients treated with 3.0 g of Hetacillin by oral route, in a single dosis, and in 93% of 85 patients treated with one single intramuscular injection of Hetacillin (1.0 g). Discharge has disappeared in an average of 48 hours in both schedules of treatment. No side effects or toxicity were observed.

Foram tratados 70 pacientes do sexo masculino portadores de uretrite gonocócica aguda com 3,0 g de Ampicilina K por via oral, em dose única. Em 87,1% dos casos houve desaparecimento da secreção uretral; na grande maioria dos casos entre 24 e 72 horas. Considerados mais 3 casos em que houve persistência da secreção pós tratamento, mas com ausência de gonococos aos exames bacteriológicos (cura bacteriológica) o sucesso terapêutico pode ser elevado para 91,4%.

Seventy male patients with acute gonorrhea with 3.0 g of Ampicillin K in a single oral dose were treated. Discharge disappeared in 87.1% of cases, in an average of 24-72 hours (clinical cure). Three cases (4.3%) showed a light mucous hialine discharge with no N. gonorrhoeae (bacteriological cure). Urethral discharge persisted in 6 patients (8.6%) with N. gonorhoeae in smears and culture (Failure). Clinical and/or bacteriological cure were observed in 64 patients (91.4%).

Foram tratados 70 pacientes do sexo masculino portadores de uretrite gonocócica aguda com 3,0 g de Ampicilina K por via oral, em dose única. Em 87,1% dos casos houve desaparecimento da secreção uretral; na grande maioria dos casos entre 24 e 72 horas. Considerados mais 3 casos em que houve persistência da secreção pós tratamento, mas com ausência de gonococos aos exames bacteriológicos (cura bacteriológica) o sucesso terapêutico pode ser elevado para 91,4%.

Seventy male patients with acute gonorrhea with 3.0 g of Ampicillin K in a single oral dose were treated. Discharge disappeared in 87.1% of cases, in an average of 24-72 hours (clinical cure). Three cases (4.3%) showed a light mucous hialine discharge with no N. gonorrhoeae (bacteriological cure). Urethral discharge persisted in 6 patients (8.6%) with N. gonorhoeae in smears and culture (Failure). Clinical and/or bacteriological cure were observed in 64 patients (91.4%).